PKRRATING - AN OVERVIEW

3B). R526 through the loop concerning αJ and αI anchors the C-terminal part of the activation loop by forming a salt bridge with E458 at The bottom of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the principle chain carbonyl of R413. The suggestion in the activation section is stabilized by a hydrogen bond involving Y454 and E480 fro